In light of the global pandemic, Full Frame will present an online showcase of documentary films. The 2022 program will feature a smaller lineup of new titles, approximately 20 features and 15 shorts. The festival will also present a variety of awards with cash prizes.

The festival is a program of the Center for Documentary Studies, a nonprofit 501(c)(3), and serves as a qualifying festival for the Producers Guild of America Award for Best Documentary and the Academy Award for Best Documentary Short Subject. The Presenting Sponsor of the festival is Duke University.